Activating Compound | Comment | Organism | Structure |
---|---|---|---|
ethanol | activates | Homo sapiens | |
ethylene glycol | little activating effect, except at high concentrations, 1 M | Homo sapiens | |
ethylene glycol monoethyl ether | little activating effect, except at high concentrations, 1 M | Homo sapiens | |
methanol | activates | Homo sapiens | |
n-butanol | 0.1 M, increases activity | Homo sapiens |
General Stability | Organism |
---|---|
dialysis using nitrocellulose membranes causes a significant loss of activity | Homo sapiens |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
Dimethylsulfoxide | - |
Homo sapiens | |
diphenyl carbonate | - |
Homo sapiens | |
n-butanol | 1 M | Homo sapiens | |
NaF | - |
Homo sapiens | |
organophosphate compounds | - |
Homo sapiens | |
paraoxon | - |
Homo sapiens | |
phenol | - |
Homo sapiens | |
PMSF | - |
Homo sapiens | |
triphenyl phosphate | - |
Homo sapiens |
KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
0.1 | - |
2-Nitrophenyl butyrate | - |
Homo sapiens | |
0.125 | - |
4-nitrophenyl pentanoate | - |
Homo sapiens | |
0.16 | - |
1-naphthyl acetate | - |
Homo sapiens | |
0.33 | - |
1-naphthyl butyrate | - |
Homo sapiens |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
membrane | - |
Homo sapiens | 16020 | - |
Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|
60000 | - |
3 * 60000, SDS-PAGE | Homo sapiens |
200000 | - |
gel filtration | Homo sapiens |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
at least 4 major isoenzymes in blood monocytes | - |
Posttranslational Modification | Comment | Organism |
---|---|---|
side-chain modification | contains an N-linked high mannose type carbohydrate chain. Two glucosamine and eight mannose molecules per mol of enzyme | Homo sapiens |
Purification (Comment) | Organism |
---|---|
- |
Homo sapiens |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
monocyte | at least 4 major isoenzymes | Homo sapiens | - |
Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
---|---|---|---|
additional information | - |
- |
Homo sapiens |
Storage Stability | Organism |
---|---|
-80°C, 10% glycerol, stable for months | Homo sapiens |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
1-naphthyl acetate + H2O | - |
Homo sapiens | 1-naphthol + acetate | - |
? | |
1-naphthyl butyrate + H2O | - |
Homo sapiens | 1-naphthol + butyrate | - |
? | |
2-nitrophenyl butyrate + H2O | - |
Homo sapiens | 2-nitrophenol + butyrate | - |
? | |
4-nitrophenyl butyrate + H2O | - |
Homo sapiens | 4-nitrophenol + butyrate | - |
? | |
4-nitrophenyl pentanoate + H2O | - |
Homo sapiens | 4-nitrophenol + pentanoate | - |
? |
Subunits | Comment | Organism |
---|---|---|
trimer | 3 * 60000, SDS-PAGE | Homo sapiens |
pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
---|---|---|---|
8 | - |
hydrolysis of 1-naphthyl butyrate | Homo sapiens |
pH Minimum | pH Maximum | Comment | Organism |
---|---|---|---|
6 | 12 | less than 50% of maximal activity at pH less than 6 or more than 12 | Homo sapiens |