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Literature summary for 2.8.2.4 extracted from

  • Ihunnah, C.A.; Wada, T.; Philips, B.J.; Ravuri, S.K.; Gibbs, R.B.; Kirisci, L.; Rubin, J.P.; Marra, K.G.; Xie, W.
    Estrogen sulfotransferase/SULT1E1 promotes human adipogenesis (2014), Mol. Cell. Biol., 34, 1682-1694.
    View publication on PubMedView publication on EuropePMC

Application

Application Comment Organism
medicine there is a positive correlation between the enzyme expression and body mass index Homo sapiens

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
3'-phosphoadenylyl sulfate + estrone Homo sapiens
-
adenosine 3',5'-bisphosphate + estrone 3-sulfate
-
?

Organism

Organism UniProt Comment Textmining
Homo sapiens P49888
-
-

Source Tissue

Source Tissue Comment Organism Textmining
adipose tissue
-
Homo sapiens
-
adipose-derived stem cell
-
Homo sapiens
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3'-phosphoadenylyl sulfate + estrone
-
Homo sapiens adenosine 3',5'-bisphosphate + estrone 3-sulfate
-
?

Synonyms

Synonyms Comment Organism
EST
-
Homo sapiens
estrogen sulfotransferase
-
Homo sapiens
SULT1E1
-
Homo sapiens

Expression

Organism Comment Expression
Homo sapiens the enzyme expression is low in preadipocytes but increases upon differentiation up

General Information

General Information Comment Organism
physiological function the enzyme promotes human adipogenesis Homo sapiens