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Literature summary for 2.8.1.2 extracted from

  • Modis, K.; Asimakopoulou, A.; Coletta, C.; Papapetropoulos, A.; Szabo, C.
    Oxidative stress suppresses the cellular bioenergetic effect of the 3-mercaptopyruvate sulfurtransferase/hydrogen sulfide pathway (2013), Biochem. Biophys. Res. Commun., 433, 401-407.
    View publication on PubMed
Search for more literature for 2.8.1.2

Cloned(Commentary)

Cloned (Comment) Organism
expressed in Escherichia coli BL21(DE3) Codon Plus cells Mus musculus

Inhibitors

Inhibitors Comment Organism Structure
hydrogen peroxide hydrogen peroxide (0.1-0.5 mM) causes a concentration-dependent decrease in the activity of recombinant enzyme (54% inhibition at 0.1 mM, 87% inhibition at 0.5 mM) Mus musculus

Localization

Localization Comment Organism GeneOntology No. Textmining
mitochondrion
-
 Mus musculus 5739
-

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
60000
-
 gel filtration Mus musculus

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
3-mercaptopyruvate + cyanide Mus musculus
-
 pyruvate + thiocyanate
-
 ?

Organism

Organism UniProt Comment Textmining
Mus musculus
-
-
-

Oxidation Stability

Oxidation Stability Organism
oxidative stress (0.1-0.5 mM H2O2) inhibits enzyme activity Mus musculus

Purification (Commentary)

Purification (Comment) Organism
GSTrap FF affinity column chromatography Mus musculus

Source Tissue

Source Tissue Comment Organism Textmining
Hepa-1c1c7 cell
-
 Mus musculus
-
liver
-
 Mus musculus
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3-mercaptopyruvate + cyanide
-
 Mus musculus pyruvate + thiocyanate
-
 ?

Synonyms

Synonyms Comment Organism
3-MST
-
 Mus musculus