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Literature summary for 2.8.1.2 extracted from
- Specificity studies of 3-mercaptopyruvate sulfurtransferase (1995), J. Biochem. Toxicol., 10, 287-292.
Activating Compound
| Activating Compound | Comment | Organism | Structure |
|---|---|---|---|
| dithiothreitol | activates from 0.4 mM to 2 mM at a 3-mercaptopyruvate concentration of 0.625 mM, inhibition at 3 mM and 4 mM dithiothreitol | Bos taurus |  |
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| 2-mercaptopropionic acid | uncompetitive inhibitor with respect to 3-mercaptopyruvate | Bos taurus | |
| 3-Mercaptopropionic acid | non-competitive inhibitor | Bos taurus | |
| dithiothreitol | inhibits from 3 mM to 4 mM at a 3-mercaptopyruvate concentration of 15 mM | Bos taurus | |
Molecular Weight [Da]
| Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
|---|---|---|---|
| 32000 | - |
SDS-PAGE | Bos taurus |
Natural Substrates/ Products (Substrates)
| Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| 3-mercaptopyruvate + cyanide | Bos taurus | - |
pyruvate + thiocyanate | - |
? | |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Bos taurus | - |
- |
- |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| kidney | - |
Bos taurus | - |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| 3-mercaptopyruvate + cyanide | - |
Bos taurus | pyruvate + thiocyanate | - |
? | |
Ki Value [mM]
| Ki Value [mM] | Ki Value maximum [mM] | Inhibitor | Comment | Organism | Structure |
|---|---|---|---|---|---|
| 17 | - |
3-Mercaptopropionic acid | pH 8, 30°C | Bos taurus | |
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