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Literature summary for 2.7.9.3 extracted from

  • Kim, T.S.; Yu, M.H.; Chung, Y.W.; Kim, J.; Choi, E.J.; Ahn, K.; Kim, I.Y.
    Fetal mouse selenophosphate synthetase 2 (SPS2): biological activities of mutant forms in Escherichia coli (1999), Mol. Cells, 9, 422-428.
    View publication on PubMed
Search for more literature for 2.7.9.3

Cloned(Commentary)

Cloned (Comment) Organism
the mutated sps2 gene, which contains cysteine in the place of the TGA encoded selenocysteine in the wild-type, is expressed in Escherichia coli selD deficient mutant, MB08. Like the Escherichia coli wild-type selD gene, the mutant spos2 gene complements the selD mutation. Replacement of Cys with either Ala, Ser, or Thr results in a loss of ability to complement the selD mutation Mus musculus

KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
0.75
-
 ATP SPS2-CYS protein expressed in Escherichia coli Mus musculus

Metals/Ions

Metals/Ions Comment Organism Structure
Mg2+ mouse SPS2-CYS expressed in Escherichia coli requires Mg2+, a molar ratio of Mg2+ to ATP in the range 2:1 or 4:1 is optimal Mus musculus

Organism

Organism UniProt Comment Textmining
Mus musculus
-
-
-

Purification (Commentary)

Purification (Comment) Organism
-
 Mus musculus

Source Tissue

Source Tissue Comment Organism Textmining

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
ATP + selenide + H2O
-
 Mus musculus AMP + selenophosphate + phosphate
-
 ?

Synonyms

Synonyms Comment Organism
selenophosphate synthetase 2
-
 Mus musculus
Sps2
-
 Mus musculus