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Literature summary for 2.7.8.5 extracted from
- Phosphatidylglycerophosphate synthase from yeast (1997), Biochim. Biophys. Acta, 1348, 187-191.
KM Value [mM]
| KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
|---|---|---|---|---|---|
| 0.026 | - |
glycerol 3-phosphate | - |
Schizosaccharomyces pombe |  |
| 0.027 | - |
glycerol 3-phosphate | - |
Saccharomyces cerevisiae | |
| 0.033 | - |
CDP-diacylglycerol | - |
Saccharomyces cerevisiae | |
| 0.13 | - |
CDP-diacylglycerol | - |
Schizosaccharomyces pombe | |
Localization
| Localization | Comment | Organism | GeneOntology No. | Textmining |
|---|---|---|---|---|
| mitochondrion | inner membrane | Saccharomyces cerevisiae | 5739 | - |
| mitochondrion | inner membrane | Schizosaccharomyces pombe | 5739 | - |
Natural Substrates/ Products (Substrates)
| Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| CDP-1,2-diacyl-sn-glycerol + glycerol 3-phosphate | Saccharomyces cerevisiae | first enzyme of cardiolipin biosynthetic pathway | ? | - |
? | |
| CDP-1,2-diacyl-sn-glycerol + glycerol 3-phosphate | Schizosaccharomyces pombe | first enzyme of cardiolipin biosynthetic pathway | ? | - |
? | |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Saccharomyces cerevisiae | - |
- |
- |
| Schizosaccharomyces pombe | - |
- |
- |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| CDP-1,2-diacyl-sn-glycerol + glycerol 3-phosphate | first enzyme of cardiolipin biosynthetic pathway | Saccharomyces cerevisiae | ? | - |
? | |
| CDP-1,2-diacyl-sn-glycerol + glycerol 3-phosphate | first enzyme of cardiolipin biosynthetic pathway | Schizosaccharomyces pombe | ? | - |
? | |
| CDP-diacylglycerol + sn-glycero-3-phosphate | - |
Schizosaccharomyces pombe | CMP + phosphatidylglycerophosphate | - |
? | |
| CDP-diacylglycerol + sn-glycerol 3-phosphate | - |
Saccharomyces cerevisiae | CMP + 3(3-sn-phosphatidyl)-sn-glycerol 1-phosphate | - |
? | |
Temperature Optimum [°C]
| Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
|---|---|---|---|
| 30 | - |
- |
Saccharomyces cerevisiae |
| 30 | - |
- |
Schizosaccharomyces pombe |
| 35 | - |
- |
Schizosaccharomyces pombe |
pH Optimum
| pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
|---|---|---|---|
| 7 | - |
- |
Saccharomyces cerevisiae |
| 7 | - |
- |
Schizosaccharomyces pombe |
| 7.5 | - |
- |
Schizosaccharomyces pombe |
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Release 2023.1 (January 2023)
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