Cloned (Comment) | Organism |
---|---|
expression of wild-type enzyme and mutant enzymes D115N, D116N and D267N as C-terminal hexahistidine fusion proteins | Escherichia coli |
Protein Variants | Comment | Organism |
---|---|---|
D115N | mutatio eliminates translocase 1 activity | Escherichia coli |
D116N | mutatio eliminates translocase 1 activity | Escherichia coli |
D267N | mutatio eliminates translocase 1 activity | Escherichia coli |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
UDP-Mur2Ac(oyl-L-Ala-D-gamma-Glu-L-Lys-D-Ala-D-Ala) + undecaprenyl phosphate | Escherichia coli | catalyzes the first of a sequence of lipid-linked steps that ultimately assemble the peptidoglycan layer of the bacterial cell wall | UMP + Mur2Ac(oyl-L-Ala-D-gamma-Glu-L-Lys-D-Ala-D-Ala)-diphosphoundecaprenol | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Escherichia coli | - |
- |
- |
Purification (Comment) | Organism |
---|---|
partial | Escherichia coli |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
UDP-Mur2Ac(oyl-L-Ala-D-gamma-Glu-L-Lys-D-Ala-D-Ala) + undecaprenyl phosphate | catalyzes the first of a sequence of lipid-linked steps that ultimately assemble the peptidoglycan layer of the bacterial cell wall | Escherichia coli | UMP + Mur2Ac(oyl-L-Ala-D-gamma-Glu-L-Lys-D-Ala-D-Ala)-diphosphoundecaprenol | - |
? |
Synonyms | Comment | Organism |
---|---|---|
phospho-N-acetyl-muramyl-pentapeptide translocase | - |
Escherichia coli |
translocase 1 | - |
Escherichia coli |