Cloned (Comment) | Organism |
---|---|
expression in Escherichia coli | Caenorhabditis elegans |
expression in Escherichia coli | Homo sapiens |
expression in Escherichia coli | Mus musculus |
KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
0.002 | - |
GDP-alpha-D-glucose | pH 7.5, 31°C | Homo sapiens | |
0.01 | - |
GDP-alpha-D-glucose | pH 7.5, 26°C | Caenorhabditis elegans | |
1.2 | - |
phosphate | pH 7.5, 26°C | Caenorhabditis elegans | |
2.9 | - |
phosphate | pH 7.5, 31°C | Homo sapiens |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
GDP-alpha-D-glucose + phosphate | Homo sapiens | - |
alpha-D-glucose 1-phosphate + GDP | - |
? | |
GDP-alpha-D-glucose + phosphate | Mus musculus | - |
alpha-D-glucose 1-phosphate + GDP | - |
? | |
GDP-alpha-D-glucose + phosphate | Caenorhabditis elegans | the enzyme may be involved in prevention of misincorporation of glucose in place of mannose residues into glycoconjugates i.e. to remove accidentally produced GDP-alpha-D-glucose | alpha-D-glucose 1-phosphate + GDP | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Caenorhabditis elegans | Q5ZR76 | - |
- |
Homo sapiens | Q6ZNW5 | - |
- |
Mus musculus | Q3TLS3 | - |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
anterior hypodermis | - |
Caenorhabditis elegans | - |
brain | highest levels measured in brain and testis (4-8 times higher than in the remaining tissues) | Mus musculus | - |
embryo | developing | Caenorhabditis elegans | - |
heart | highest levels measured in brain and testis (4-8 times higher than in the remaining tissues) | Mus musculus | - |
kidney | highest levels measured in brain and testis (4-8 times higher than in the remaining tissues) | Mus musculus | - |
larva | expressed in all the normal larval stages observed | Caenorhabditis elegans | - |
liver | highest levels measured in brain and testis (4-8 times higher than in the remaining tissues) | Mus musculus | - |
spermatheca | - |
Caenorhabditis elegans | - |
testis | highest levels measured in brain and testis (4-8 times higher than in the remaining tissues) | Mus musculus | - |
thymus | highest levels measured in brain and testis (4-8 times higher than in the remaining tissues) | Mus musculus | - |
Storage Stability | Organism |
---|---|
-80°C, 10% glycerol | Caenorhabditis elegans |
-80°C, 10% glycerol | Homo sapiens |
-80°C, 10% glycerol | Mus musculus |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
GDP-alpha-D-glucose + phosphate | - |
Homo sapiens | alpha-D-glucose 1-phosphate + GDP | - |
? | |
GDP-alpha-D-glucose + phosphate | - |
Mus musculus | alpha-D-glucose 1-phosphate + GDP | - |
? | |
GDP-alpha-D-glucose + phosphate | the enzyme may be involved in prevention of misincorporation of glucose in place of mannose residues into glycoconjugates i.e. to remove accidentally produced GDP-alpha-D-glucose | Caenorhabditis elegans | alpha-D-glucose 1-phosphate + GDP | - |
? | |
GDP-alpha-D-glucose + phosphate | activities with GDP-L-galactose, GDP-D-mannose and UDP-D-glucose are all less than 3% that with GDP-D-glucose | Caenorhabditis elegans | alpha-D-glucose 1-phosphate + GDP | - |
? | |
GDP-alpha-D-glucose + phosphate | activities with GDP-L-galactose, GDP-D-mannose and UDP-D-glucose are all less than 3% that with GDP-D-glucose | Homo sapiens | alpha-D-glucose 1-phosphate + GDP | - |
? |
Synonyms | Comment | Organism |
---|---|---|
C10F3.4 | - |
Caenorhabditis elegans |
C15orf58 | - |
Homo sapiens |
Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
---|---|---|---|
26 | - |
assay at | Caenorhabditis elegans |
Turnover Number Minimum [1/s] | Turnover Number Maximum [1/s] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
26 | - |
GDP-alpha-D-glucose | pH 7.5, 31°C | Homo sapiens | |
28.1 | - |
phosphate | pH 7.5, 31°C | Homo sapiens | |
265 | - |
GDP-alpha-D-glucose | pH 7.5, 26°C | Caenorhabditis elegans | |
380 | - |
phosphate | pH 7.5, 26°C | Caenorhabditis elegans |
pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
---|---|---|---|
7.5 | - |
assay at | Caenorhabditis elegans |
kcat/KM Value [1/mMs-1] | kcat/KM Value Maximum [1/mMs-1] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
9.7 | - |
phosphate | pH 7.5, 31°C | Homo sapiens | |
317 | - |
phosphate | pH 7.5, 26°C | Caenorhabditis elegans | |
1300 | - |
GDP-alpha-D-glucose | pH 7.5, 31°C | Homo sapiens | |
26500 | - |
GDP-alpha-D-glucose | pH 7.5, 26°C | Caenorhabditis elegans |