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Literature summary for 2.7.7.7 extracted from
- Translesion synthesis of abasic sites by yeast DNA polymerase epsilon (2009), J. Biol. Chem., 284, 31555-31563.
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Saccharomyces cerevisiae | - |
- |
- |
Purification (Commentary)
| Purification (Comment) | Organism |
|---|---|
| ammonium sulfate precipitation, glutathione-Sepharose column chromatography, Mono-Q column chromatography, and Superose 6 gel filtration | Saccharomyces cerevisiae |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| deoxynucleoside triphosphate + DNAn | - |
Saccharomyces cerevisiae | diphosphate + DNAn+1 | - |
? |  |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| DNA polymerase 2 | - |
Saccharomyces cerevisiae |
| DNA polymerase epsilon | - |
Saccharomyces cerevisiae |
| POl epsilon | - |
Saccharomyces cerevisiae |
| Pol2 | - |
Saccharomyces cerevisiae |
General Information
| General Information | Comment | Organism |
|---|---|---|
| physiological function | DNA polymerase epsilon with 3'-5' proofreading exonuclease activity bypasses only the model abasic site during processive synthesis and cannot reinitiate DNA synthesis | Saccharomyces cerevisiae |
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