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Literature summary for 2.7.7.7 extracted from

  • Pohlhaus, J.R.; Long, D.T.; OReilly, E.; Kreuzer, K.N.
    The epsilon subunit of DNA polymerase III is involved in the nalidixic acid-induced SOS response in Escherichia coli (2008), J. Bacteriol., 190, 5239-5247.
    View publication on PubMedView publication on EuropePMC

Protein Variants

Protein Variants Comment Organism
additional information insertions in the DNA polymerase III epsilon subunit gene (dnaQ) cause a specific defect in SOS induction by nalidixic acid but not by mitomycin C Escherichia coli

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
deoxynucleoside triphosphate + DNAn Escherichia coli
-
diphosphate + DNAn+1
-
?
deoxynucleoside triphosphate + DNAn Escherichia coli JH39
-
diphosphate + DNAn+1
-
?

Organism

Organism UniProt Comment Textmining
Escherichia coli
-
-
-
Escherichia coli JH39
-
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
deoxynucleoside triphosphate + DNAn
-
Escherichia coli diphosphate + DNAn+1
-
?
deoxynucleoside triphosphate + DNAn
-
Escherichia coli JH39 diphosphate + DNAn+1
-
?

Synonyms

Synonyms Comment Organism
DNA polymerase III epsilon subunit 3'-to-5' proofreading exonuclease of the holoenzyme Escherichia coli
pol III
-
Escherichia coli