Protein Variants | Comment | Organism |
---|---|---|
D112A/E114A | the mutant T4 DNA polymerases is defective in 3'-5' exonuclease activity and has a 1000fold increase in the development of spontaneous mutations compared to wild type polymerase | Tequatrovirus T4 |
D219A | the mutant T4 DNA polymerases is defective in 3'-5' exonuclease activity and has a 1000fold increase in the development of spontaneous mutations compared to wild type polymerase | Tequatrovirus T4 |
D324A | the mutant T4 DNA polymerases is defective in 3'-5' exonuclease activity and has a 1000fold increase in the development of spontaneous mutations compared to wild type polymerase, the exonuclease activity of the D324A mutant is 100000-fold lower than wild type polymerase | Tequatrovirus T4 |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Bacillus subtilis | - |
- |
- |
Escherichia coli | - |
- |
- |
Escherichia phage RB69 | - |
- |
- |
Escherichia phage T7 | - |
- |
- |
Geobacillus stearothermophilus | - |
- |
- |
Homo sapiens | - |
- |
- |
Tequatrovirus T4 | - |
- |
- |
Thermus aquaticus | P19821 | - |
- |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
deoxynucleoside triphosphate + DNAn | - |
Bacillus subtilis | diphosphate + DNAn+1 | - |
? | |
deoxynucleoside triphosphate + DNAn | - |
Escherichia coli | diphosphate + DNAn+1 | - |
? | |
deoxynucleoside triphosphate + DNAn | - |
Homo sapiens | diphosphate + DNAn+1 | - |
? | |
deoxynucleoside triphosphate + DNAn | - |
Geobacillus stearothermophilus | diphosphate + DNAn+1 | - |
? | |
deoxynucleoside triphosphate + DNAn | - |
Tequatrovirus T4 | diphosphate + DNAn+1 | - |
? | |
deoxynucleoside triphosphate + DNAn | - |
Escherichia phage T7 | diphosphate + DNAn+1 | - |
? | |
deoxynucleoside triphosphate + DNAn | - |
Escherichia phage RB69 | diphosphate + DNAn+1 | - |
? | |
deoxynucleoside triphosphate + DNAn | - |
Thermus aquaticus | diphosphate + DNAn+1 | - |
? |
Synonyms | Comment | Organism |
---|---|---|
DNA polymerase | - |
Bacillus subtilis |
DNA polymerase | - |
Escherichia coli |
DNA polymerase | - |
Geobacillus stearothermophilus |
DNA polymerase | - |
Tequatrovirus T4 |
DNA polymerase | - |
Escherichia phage T7 |
DNA polymerase | - |
Escherichia phage RB69 |
DNA polymerase | - |
Thermus aquaticus |
DNA polymerase I | - |
Homo sapiens |
Pol | - |
Bacillus subtilis |
Pol | - |
Escherichia coli |
Pol | - |
Geobacillus stearothermophilus |
Pol | - |
Tequatrovirus T4 |
Pol | - |
Escherichia phage T7 |
Pol | - |
Escherichia phage RB69 |
Pol | - |
Thermus aquaticus |
Pol I | - |
Homo sapiens |