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Literature summary for 2.7.7.7 extracted from

  • Goodman, M.F.; Fygenson, D.K.
    DNA polymerase fidelity: from genetics toward a biochemical understanding (1998), Genetics, 148, 1475-1482.
    View publication on PubMedView publication on EuropePMC
Search for more literature for 2.7.7.7

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
deoxynucleoside triphosphate + DNAn Escherichia coli
-
 diphosphate + DNAn+1
-
 ?
deoxynucleoside triphosphate + DNAn Tequatrovirus T4
-
 diphosphate + DNAn+1
-
 ?

Organism

Organism UniProt Comment Textmining
Escherichia coli
-
-
-
Tequatrovirus T4
-
 mutator and antimutator strains
-

Reaction

Reaction Comment Organism Reaction ID
a 2'-deoxyribonucleoside 5'-triphosphate + DNAn = diphosphate + DNAn+1 mechanism Escherichia coli
a
a 2'-deoxyribonucleoside 5'-triphosphate + DNAn = diphosphate + DNAn+1 mechanism Tequatrovirus T4
a

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
deoxynucleoside triphosphate + DNAn
-
 Escherichia coli diphosphate + DNAn+1
-
 ?
deoxynucleoside triphosphate + DNAn
-
 Tequatrovirus T4 diphosphate + DNAn+1
-
 ?
deoxynucleoside triphosphate + DNAn exonuclease 3'--5' activity, pol I Escherichia coli diphosphate + DNAn+1
-
 ?
deoxynucleoside triphosphate + DNAn exonuclease 3'--5', phage T4-induced DNA polymerase Tequatrovirus T4 diphosphate + DNAn+1
-
 ?