Activating Compound | Comment | Organism | Structure |
---|---|---|---|
sigma70 | the sigma factor increases the transcription efficiency of templates with nonphysiological nonprokaryotic promoters | Escherichia coli |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
CBR703 | the IC50s values are significantly decreased with template Kool NC-45, or increased with template poly(dA-dT) | Escherichia coli | |
corallopyronin | inhibition is not affected by template Kool NC-45 | Escherichia coli | |
lipiarmycin | - |
Escherichia coli | |
additional information | the use of dsDNA templates containing classical promoters has only a negligible effects on the potency of enzyme inhibitors | Escherichia coli | |
myxopyronin | an alpha-pyrone antibiotic, targets the RNAP switch region, which is the hinge that mediates opening and closing of the RNAP active-center cleft. Lower values for inhibition by myxopyronin in the presence of template Kool NC-45 | Escherichia coli |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Escherichia coli | - |
- |
- |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
additional information | dsDNA templates used for activity are T7A1_763, T7A1_437, T7A1_149, pcDNA3.1, pGEM, T-phage DNA, Escherichia coli DNA, calf thymus DNA, poly(dA-dT), and Kool NC-45 | Escherichia coli | ? | - |
? |
Synonyms | Comment | Organism |
---|---|---|
RNAP | - |
Escherichia coli |