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Literature summary for 2.7.7.50 extracted from

  • Hausmann, S.; Altura, M.A.; Witmer, M.; Singer, S.M.; Elmendorf, H.G.; Shuman, S.
    Yeast-like mRNA capping apparatus in Giardia lamblia (2005), J. Biol. Chem., 280, 12077-12086.
    View publication on PubMed
Search for more literature for 2.7.7.50

KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
additional information
-
 additional information half-maximal guanylylation is achieved at 0.00009 mM GTP Giardia intestinalis
additional information
-
 additional information half-maximal guanylylation is achieved at 0.00009 mM GTP Cyanidioschyzon merolae

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
GTP + pp(5')RNA Giardia intestinalis
-
 G(5')ppp(5')RNA + diphosphate
-
 r
GTP + pp(5')RNA Cyanidioschyzon merolae
-
 G(5')ppp(5')RNA + diphosphate
-
 r
GTP + pp(5')RNA Cyanidioschyzon merolae CMA035C
-
 G(5')ppp(5')RNA + diphosphate
-
 r

Organism

Organism UniProt Comment Textmining
Cyanidioschyzon merolae
-
 CMA035C
-
Cyanidioschyzon merolae CMA035C
-
 CMA035C
-
Giardia intestinalis
-
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
GTP + pp(5')RNA
-
 Giardia intestinalis G(5')ppp(5')RNA + diphosphate
-
 r
GTP + pp(5')RNA
-
 Cyanidioschyzon merolae G(5')ppp(5')RNA + diphosphate
-
 r
GTP + pp(5')RNA the forward guanylylation reaction of the capping enzyme is in equilibrium with the reverse diphosphorolysis reaction, in which diphosphate attacks the enzyme-GMP complex to regenerate GMP Cyanidioschyzon merolae G(5')ppp(5')RNA + diphosphate
-
 r
GTP + pp(5')RNA the forward guanylylation reaction of the capping enzyme is in equilibrium with the reverse pyrophosphorolysis reaction, in which diphosphate attacks the enzyme-GMP complex to regenerate GMP Giardia intestinalis G(5')ppp(5')RNA + diphosphate
-
 r
GTP + pp(5')RNA
-
 Cyanidioschyzon merolae CMA035C G(5')ppp(5')RNA + diphosphate
-
 r
GTP + pp(5')RNA the forward guanylylation reaction of the capping enzyme is in equilibrium with the reverse diphosphorolysis reaction, in which diphosphate attacks the enzyme-GMP complex to regenerate GMP Cyanidioschyzon merolae CMA035C G(5')ppp(5')RNA + diphosphate
-
 r

Subunits

Subunits Comment Organism
monomer the enzyme exists as a monomer in solution Giardia intestinalis
monomer the enzyme exists as a monomer in solution Cyanidioschyzon merolae

Synonyms

Synonyms Comment Organism
capping enzyme guanylyltransferase
-
 Giardia intestinalis
capping enzyme guanylyltransferase
-
 Cyanidioschyzon merolae
CmCeg1
-
 Cyanidioschyzon merolae
GlCeg1
-
 Giardia intestinalis
More mRNA capping apparatus consists of separate triphosphatase and guanylyltransferase components (GlCeg1) Giardia intestinalis
More mRNA capping apparatus consists of separate triphosphatase and guanylyltransferase components (GlCeg1) Cyanidioschyzon merolae