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Literature summary for 2.7.7.49 extracted from

  • Benetti, R.; Gonzalo, S.; Jaco, I.; Munoz, P.; Gonzalez, S.; Schoeftner, S.; Murchison, E.; Andl, T.; Chen, T.; Klatt, P.; Li, E.; Serrano, M.; Millar, S.; Hannon, G.; Blasco, M.A.
    A mammalian microRNA cluster controls DNA methylation and telomere recombination via Rbl2-dependent regulation of DNA methyltransferases (2008), Nat. Struct. Mol. Biol., 15, 268-279.
    View publication on PubMedView publication on EuropePMC

Inhibitors

Inhibitors Comment Organism Structure
additional information decreased telomerase activity and normal expression of telomere-binding proteins in the absence of Dicer Mus musculus

Organism

Organism UniProt Comment Textmining
Mus musculus
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
embryonic stem cell
-
Mus musculus
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
deoxynucleoside triphosphate + DNAn
-
Mus musculus diphosphate + DNAn+1
-
?

Synonyms

Synonyms Comment Organism
telomerase reverse transcriptase
-
Mus musculus
TERT
-
Mus musculus