Inhibitors | Comment | Organism | Structure |
---|---|---|---|
2',3'-dideoxythymidine 5'-triphosphate | Mn2+ is requisite for the compound to exhibit inhibition, competitive with dTTP | Rauscher murine leukemia virus | |
2'-deoxyxylofuranosylthymidine 5'-triphosphate | Mn2+ is requisite for the compound to exhibit inhibition, competitive with dTTP | Rauscher murine leukemia virus | |
3'-Azido-2',3'-dideoxythymidine 5'-triphosphate | Mn2+ is requisite for the compound to exhibit inhibition, competitive with dTTP | Rauscher murine leukemia virus |
KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
0.03 | - |
dTTP | pH 8.5, 37°C | Rauscher murine leukemia virus |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Rauscher murine leukemia virus | - |
- |
- |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
deoxynucleoside triphosphate + DNAn | - |
Rauscher murine leukemia virus | diphosphate + DNAn+1 | - |
? | |
dTTP + poly(rA)/(dT)18 | - |
Rauscher murine leukemia virus | ? | - |
? |
Ki Value [mM] | Ki Value maximum [mM] | Inhibitor | Comment | Organism | Structure |
---|---|---|---|---|---|
0.0018 | - |
3'-Azido-2',3'-dideoxythymidine 5'-triphosphate | pH 8.5, 37°C | Rauscher murine leukemia virus | |
0.0093 | - |
2',3'-dideoxythymidine 5'-triphosphate | pH 8.5, 37°C | Rauscher murine leukemia virus | |
0.0163 | - |
2'-deoxyxylofuranosylthymidine 5'-triphosphate | pH 8.5, 37°C | Rauscher murine leukemia virus |