Cloned (Comment) | Organism |
---|---|
expressed in Escherichia coli | Bovine viral diarrhea virus 1 |
Protein Variants | Comment | Organism |
---|---|---|
E291G | mutant is insensitive against inhibitor ethyl 2-methylimidazo[1,2-a]pyrrolo[2,3-c]pyridin-8-carboxylate | Bovine viral diarrhea virus 1 |
F224S | mutant is insensitive against inhibitors ethyl 2-methylimidazo[1,2-a]pyrrolo[2,3-c]pyridin-8-carboxylate, 5-[(4-bromophenyl)methyl]-2-phenyl-5H-imidazo[4,5-c]pyridine, and VP32947 | Bovine viral diarrhea virus 1 |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
1-[2-(diethylamino)ethyl]-6-(1H-imidazol-1-yl)-1,3-dihydro-2H-benzimidazol-2-one | - |
Bovine viral diarrhea virus 1 | |
5-[(4-bromophenyl)methyl]-2-phenyl-5H-imidazo[4,5-c]pyridine | - |
Bovine viral diarrhea virus 1 | |
ethyl 2-methylimidazo[1,2-a]pyrrolo[2,3-c]pyridin-8-carboxylate | AG110, potent inhibitor of pestivirus replication, does not inhibit the in vitro activity of recombinant bovine viral diarrhea virus RdRp but inhibits the activity of bovine viral diarrhea virus replication complexes | Bovine viral diarrhea virus 1 | |
N-propyl-N-[2-(2H-1,2,4-triazino[5,6-b]indol-3-ylthio)ethyl]-1-propanamine | VP32947 | Bovine viral diarrhea virus 1 |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Bovine viral diarrhea virus 1 | P19711 | strains Marloie, NADL, and 3435 | - |
Purification (Comment) | Organism |
---|---|
- |
Bovine viral diarrhea virus 1 |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
nucleoside triphosphate + RNAn | - |
Bovine viral diarrhea virus 1 | diphosphate + RNAn+1 | - |
? |
Synonyms | Comment | Organism |
---|---|---|
RDRP | - |
Bovine viral diarrhea virus 1 |
RNA-dependent RNA polymerase | - |
Bovine viral diarrhea virus 1 |