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Literature summary for 2.7.7.48 extracted from

  • Nayak, A.; Goodfellow, I.G.; Belsham, G.J.
    Factors required for the uridylylation of the foot-and-mouth disease virus 3B1, 3B2, and 3B3 peptides by the RNA-dependent RNA polymerase (3Dpol) in vitro (2005), J. Virol., 79, 7698-7706.
    View publication on PubMedView publication on EuropePMC
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Activating Compound

Activating Compound Comment Organism Structure
Foot-and-Mouth disease virus 3B1 acts as primer for RNA synthesis by RNA-dependent RNA polymerase. To act as the primer for positive-strand RNA synthesis, the peptide has to be uridylated to form VpgpU(pU). This reaction is achieved by the RNA-dependent RNA polymerase in the presence of the 3CD precursor plus an internal RNA sequence termed a cis-acting replication element, cre Foot-and-mouth disease virus
Foot-and-Mouth disease virus 3B2 acts as primer for RNA synthesis by RNA-dependent RNA polymerase. To act as the primer for positive-strand RNA synthesis, the peptide has to be uridylated to form VpgpU(pU). This reaction is achieved by the RNA-dependent RNA polymerase in the presence of the 3CD precursor plus an internal RNA sequence termed a cis-acting replication element, cre Foot-and-mouth disease virus
Foot-and-Mouth disease virus 3B3 acts as primer for RNA synthesis by RNA-dependent RNA polymerase. To act as the primer for positive-strand RNA synthesis, the peptide has to be uridylated to form VpgpU(pU). This reaction is achieved by the RNA-dependent RNA polymerase in the presence of the 3CD precursor plus an internal RNA sequence termed a cis-acting replication element, cre Foot-and-mouth disease virus
VpgpU(pU) Foot-and-Mouth disease virus 3B peptides acts as primers for RNA synthesis by RNA-dependent RNA polymerase. To act as the primer for positive-strand RNA synthesis, the peptides have to be uridylated to form VPgpU(pU). This reaction is achieved by the RNA-dependent RNA polymerase in the presence of the 3CD precursor plus an internal RNA sequence termed a cis-acting replication element, cre Foot-and-mouth disease virus

Organism

Organism UniProt Comment Textmining
Foot-and-mouth disease virus
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Synonyms

Synonyms Comment Organism
3Dpol
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 Foot-and-mouth disease virus
RNA-dependent RNA polymerase
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 Foot-and-mouth disease virus