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Literature summary for 2.7.7.48 extracted from

  • Goodin, M.M.; Schlagnhaufer, B.; Weir, T.; Romaine, C.P.
    Characterization of an RNA-dependent RNA polymerase activity associated with La France isometric virus (1997), J. Virol., 71, 2264-2269.
    View publication on PubMedView publication on EuropePMC

Inhibitors

Inhibitors Comment Organism Structure
additional information the enzyme is resistant to inhibitors of DNA-dependent RNA polymerase activity: actinomycin D, alpha-amanitin and rifampin La France isometric virus

Metals/Ions

Metals/Ions Comment Organism Structure
Mg2+ maximal activity in presence of La France isometric virus

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
nucleoside triphosphate + RNAn La France isometric virus the enzyme is probably a transcriptase engaged in the synthesis of ssRNA transcripts corresponding to each of the virion-associated dsRNAs diphosphate + RNAn+1
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?

Organism

Organism UniProt Comment Textmining
La France isometric virus
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Agaricus bisporus infected with
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Purification (Commentary)

Purification (Comment) Organism
-
La France isometric virus

Source Tissue

Source Tissue Comment Organism Textmining
additional information tissue of Agaricus bisporus La France isometric virus
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Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
nucleoside triphosphate + RNAn
-
La France isometric virus diphosphate + RNAn+1
-
?
nucleoside triphosphate + RNAn the enzyme is probably a transcriptase engaged in the synthesis of ssRNA transcripts corresponding to each of the virion-associated dsRNAs La France isometric virus diphosphate + RNAn+1
-
?