Any feedback?
Literature summary for 2.7.7.41 extracted from
- Characterization of cytidine triphosphate:phosphatidate cytidyltransferase from suspension cultured Catharanthus roseus cells (1993), Plant Sci., 88, 13-18.
No PubMed abstract available
Activating Compound
| Activating Compound | Comment | Organism | Structure |
|---|---|---|---|
| ATP | slight stimulation at high concentrations | Catharanthus roseus |  |
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| ATP | slight inhibition below 0.175 mM | Catharanthus roseus | |
| CDP | - |
Catharanthus roseus | |
| diphosphate | - |
Catharanthus roseus | |
| additional information | no inhibition by 1.65 mM ADP | Catharanthus roseus |
KM Value [mM]
| KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
|---|---|---|---|---|---|
| 0.08 | - |
phosphatidic acid | pH 7.2, 37°C | Catharanthus roseus | |
| 0.17 | - |
CTP | pH 7.2, 37°C | Catharanthus roseus | |
Localization
| Localization | Comment | Organism | GeneOntology No. | Textmining |
|---|---|---|---|---|
| chloroplast envelope | - |
Catharanthus roseus | 9941 | - |
| endoplasmic reticulum | - |
Catharanthus roseus | 5783 | - |
| microsome | - |
Catharanthus roseus | - |
- |
| plasma membrane | - |
Catharanthus roseus | 5886 | - |
Metals/Ions
| Metals/Ions | Comment | Organism | Structure |
|---|---|---|---|
| Ca2+ | activates at low concentrations, decrease in activity at higher concentrations | Catharanthus roseus | |
| Co2+ | activates at low concentrations, decrease in activity at higher concentrations | Catharanthus roseus | |
| Mg2+ | maximal activation, about 15fold, at 10 mM | Catharanthus roseus | |
| Mn2+ | maximal activation, about 10fold, at 1 mM | Catharanthus roseus | |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Catharanthus roseus | - |
- |
- |
Purification (Commentary)
| Purification (Comment) | Organism |
|---|---|
- |
Catharanthus roseus |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| cell suspension culture | - |
Catharanthus roseus | - |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| CTP + phosphatidate | - |
Catharanthus roseus | diphosphate + CDPdiacylglycerol | - |
? | |
pH Optimum
| pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
|---|---|---|---|
| 7.3 | - |
- |
Catharanthus roseus |
Ki Value [mM]
| Ki Value [mM] | Ki Value maximum [mM] | Inhibitor | Comment | Organism | Structure |
|---|---|---|---|---|---|
| 0.24 | - |
CDP | pH 7.2, 37°C | Catharanthus roseus | |
| 1.5 | - |
diphosphate | pH 7.2, 37°C | Catharanthus roseus | |
Use of this online version of BRENDA is free under the CC BY 4.0 license. See terms of use for full details.
Release 2023.1 (January 2023)
Legal
Curated at
Member of
