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Literature summary for 2.7.7.38 extracted from

  • Yoon, H.J.; Ku, M.J.; Mikami, B.; Suh, S.W.
    Structure of 3-deoxy-manno-octulosonate cytidylyltransferase from Haemophilus influenzae complexed with the substrate 3-deoxy-manno-octulosonate in the beta-configuration (2008), Acta Crystallogr. Sect. D, 64, 1292-1294.
    View publication on PubMed

Application

Application Comment Organism
medicine the structure of 3-deoxy-manno-octulosonate cytidylyltransferase from Haemophilus influenzae in complex with 3-deoxy-manno-octulosonate will be useful in structure-based inhibitor design Haemophilus influenzae

Crystallization (Commentary)

Crystallization (Comment) Organism
the structure of 3-deoxy-manno-octulosonate cytidylyltransferase from Haemophilus influenzae complexed with the substrate 3-deoxy-manno-octulosonate is determined at 2.30 A resolution Haemophilus influenzae

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
CTP + 3-deoxy-D-manno-octulosonate Haemophilus influenzae
-
diphosphate + CMP-3-deoxy-D-manno-octulosonate
-
?

Organism

Organism UniProt Comment Textmining
Haemophilus influenzae P44490
-
-

Purification (Commentary)

Purification (Comment) Organism
-
Haemophilus influenzae

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
CTP + 3-deoxy-D-manno-octulosonate
-
Haemophilus influenzae diphosphate + CMP-3-deoxy-D-manno-octulosonate
-
?

Subunits

Subunits Comment Organism
homodimer
-
Haemophilus influenzae

Synonyms

Synonyms Comment Organism
3-deoxy-manno-octulosonate cytidylyltransferase
-
Haemophilus influenzae
CKS
-
Haemophilus influenzae
CMP-KDO synthetase
-
Haemophilus influenzae