Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary for 2.7.7.31 extracted from

  • Boubakour-Azzouz, I.; Bertrand, P.; Claes, A.; Lopez, B.S.; Rougeon, F.
    Terminal deoxynucleotidyl transferase requires KU80 and XRCC4 to promote N-addition at non-V(D)J chromosomal breaks in non-lymphoid cells (2012), Nucleic Acids Res., 40, 8381-8391.
    View publication on PubMedView publication on EuropePMC

Organism

Organism UniProt Comment Textmining
Mus musculus P09838
-
-

General Information

General Information Comment Organism
physiological function in Chinese hamster ovary cells, ectopic expression of the enzmye efficiently promotes N-additions at the junction of chromosomal double-strand breaks generated by the meganuclease I-SceI. The size of the N-additions is comparable with that at V(D)J junctions. No N-addition is observed in KU80- or XRCC4-deficient cells Mus musculus