Literature summary for 2.7.7.23 extracted from

Guan, W.; Cai, L.; Fang, J.; Wu, B.; George Wang, P.
Enzymatic synthesis of UDP-GlcNAc/UDP-GalNAc analogs using N-acetylglucosamine 1-phosphate uridyltransferase (GlmU) (2009), Chem. Commun. (Camb. ), 2009, 6976-6978.

Search for more literature for 2.7.7.23

Organism

Organism	UniProt	Comment	Textmining
Escherichia coli	-	-	-

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
additional information	enzyme shows relaxed tolerance for modifications at N-acyl, C-3, C-4, and C-6 positions, with a preference for small substituent groups. The yields are low to moderate (10-65%) and some sugar-1-Ps fail to generate the corresponding UDP-sugars due to the steric problem	Escherichia coli	?	-	?
N-acetyl-4-deoxy-alpha-D-glucosamine 1-phosphate + UTP	-	Escherichia coli	UDP-N-acetyl-4-deoxy-alpha-D-glucosamine + diphosphate	yield: 59%	?
N-acetyl-6-deoxy-6-azido-alpha-D-glucosamine 1-phosphate + UTP	-	Escherichia coli	UDP-N-acetyl-6-deoxy-6-azido-alpha-D-glucosamine + diphosphate	yield: 20%	?
N-acetyl-6-deoxy-alpha-D-galactosamine 1-phosphate + UTP	-	Escherichia coli	UDP-N-acetyl-6-deoxy-alpha-D-galactosamine + diphosphate	yield: 55%	?
N-acetyl-6-deoxy-alpha-D-glucosamine 1-phosphate + UTP	-	Escherichia coli	UDP-N-acetyl-6-deoxy-alpha-D-glucosamine + diphosphate	yield: 50%	?
N-acetyl-alpha-D-allopyranosylamine 1-phosphate + UTP	-	Escherichia coli	UDP-N-acetyl-alpha-D-allopyranosylamine + diphosphate	yield: 20%	?
N-acetyl-alpha-D-galactosamine 1-phosphate + UTP	-	Escherichia coli	UDP-N-acetyl-alpha-D-galactosamine + diphosphate	yield: 65%	?
N-acetyl-alpha-D-glucosamine 1-phosphate + UTP	-	Escherichia coli	UDP-N-acetyl-alpha-D-glucosamine + diphosphate	yield: 40%	?
N-azidoacetyl-alpha-D-glucosamine 1-phosphate + UTP	-	Escherichia coli	UDP-N-azidoacetyl-alpha-D-glucosamine + diphosphate	yield: 44%	?
N-butanoyl-alpha-D-glucosamine 1-phosphate + UTP	-	Escherichia coli	UDP-N-butanoyl-alpha-D-glucosamine + diphosphate	yield: 27%	?
N-propanoyl-alpha-D-galactosamine 1-phosphate + UTP	-	Escherichia coli	UDP-N-propanoyl-alpha-D-galactosamine + diphosphate	yield: 10%	?
N-propanoyl-alpha-D-glucosamine 1-phosphate + UTP	-	Escherichia coli	UDP-N-propanoyl-alpha-D-glucosamine + diphosphate	yield: 57%	?

Synonyms

Synonyms	Comment	Organism
GlmU	-	Escherichia coli
N-acetylglucosamine 1-phosphate uridyltransferase	-	Escherichia coli

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Release 2023.1 (January 2023)