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Literature summary for 2.7.7.2 extracted from

  • Wu, M.; Repetto, B.; Glerum, D.M.; Tzagoloff, A.
    Cloning and characterization of FAD1, the structural gene for flavin adenine dinucleotide synthetase of Saccharomyces cerevisiae (1995), Mol. Cell. Biol., 15, 264-271.
    View publication on PubMedView publication on EuropePMC
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Cloned(Commentary)

Cloned (Comment) Organism
-
 Saccharomyces cerevisiae
structural gene FAD1, essential yeast protein, disruption of the gene induces a lethal phenotype, cloned from a genomic library, vector pATH26 transformed into Saccharomyces cerevisiae and Escherichia coli RR1 on a multicopy plasmid Saccharomyces cerevisiae

Localization

Localization Comment Organism GeneOntology No. Textmining
mitochondrion presence of mitochondrial FAD synthetase activity in strains transformed with FAD1 on a high-copy-number plasmid, but not in mitochondria of wild-type strains Saccharomyces cerevisiae 5739
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Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
36000
-
 recombinant enzyme, expressed in E. coli, PAGE Saccharomyces cerevisiae

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
ATP + FMN Saccharomyces cerevisiae
-
 diphosphate + FAD
-
 r

Organism

Organism UniProt Comment Textmining
Saccharomyces cerevisiae
-
-
-
Saccharomyces cerevisiae P38913 baker's yeast, brewers' yeast, beer yeast, FAD1 nucleotide sequence
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Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
ATP + FMN
-
 Saccharomyces cerevisiae diphosphate + FAD
-
 r