Activating Compound | Comment | Organism | Structure |
---|---|---|---|
Lipids | regulation of activity by reversible association with membrane lipids, activation of enzyme when bound to lipid vesicles, vesicles containing 1-palmitoyl-2-oleoyl-sn-glycero-3-phospho-L-serine or egg phosphatidylglycerol are more effective than vesicles containing 1,2-dioleoyl-sn-glycero-3-phosphoethanolamine, 1,2-dioleoyl-sn-glycerol, or egg phosphatidylcholine | Rattus norvegicus |
Cloned (Comment) | Organism |
---|---|
expressed in High 5 cells | Rattus norvegicus |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
membrane | enzyme is activated when bound to vesicles | Rattus norvegicus | 16020 | - |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
CTP + choline phosphate | Rattus norvegicus | rate limiting enzyme for the synthesis of phosphatidylcholine | diphosphate + CDP-choline | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Rattus norvegicus | - |
- |
- |
Posttranslational Modification | Comment | Organism |
---|---|---|
phosphoprotein | C-terminal region is highly phosphorylated, phosphorylation decreases membrane affinity and is therefore involved in regulation of enzyme activity | Rattus norvegicus |
Purification (Comment) | Organism |
---|---|
recombinant protein | Rattus norvegicus |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
liver | - |
Rattus norvegicus | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
CTP + choline phosphate | - |
Rattus norvegicus | diphosphate + CDP-choline | - |
? | |
CTP + choline phosphate | rate limiting enzyme for the synthesis of phosphatidylcholine | Rattus norvegicus | diphosphate + CDP-choline | - |
? |
Subunits | Comment | Organism |
---|---|---|
dimer | - |
Rattus norvegicus |
Synonyms | Comment | Organism |
---|---|---|
CCTalpha | - |
Rattus norvegicus |