Literature summary for 2.7.7.14 extracted from

Ando, H.; Aoyama, C.; Horibata, Y.; Satou, M.; Mitsuhashi, S.; Itoh, M.; Hosaka, K.; Sugimoto, H.
Transcriptional suppression of CTP:phosphoethanolamine cytidylyltransferase by 25-hydroxycholesterol is mediated by nuclear factor-Y and Yin Yang 1 (2015), Biochem. J., 471, 369-379.

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Organism

Organism	UniProt	Comment	Textmining
Mus musculus	-	-	-

Source Tissue

Source Tissue	Comment	Organism	Textmining
NIH-3T3 cell	-	Mus musculus	-

Expression

Organism	Comment	Expression
Mus musculus	the important element for transcriptional control of Pcyt2 by 25-HC resides between -56 and -36 in NIH 3T3 cells. Nuclear factor-Y binds at C(-37)CAAT(-41) and Yin Yang1 binds at C(-42)AT(-40) in the Pcyt2 promoter. Nuclear factor-Y is involved in the inhibitory effects of 25-hydroxycholesterol on Pcyt2 transcription	additional information

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Release 2023.1 (January 2023)