Cloned (Comment) | Organism |
---|---|
overexpression of Cavbeta1b in Xenopus laevis oocytes in inclusion bodies | Rattus norvegicus |
overexpression of Cavbeta2a in Xenopus laevis oocytes in inclusion bodies | Rattus norvegicus |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
membrane | - |
Rattus norvegicus | 16020 | - |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
additional information | Rattus norvegicus | the voltage-gated calcium channel beta1b contains a conserved guanylate kinase domain, which is alone recapitulating calcium channel beta-subunit CaVbeta-mediated modulation of channel activation facilitating inactivation of the voltage-gated channel. CaVbeta can switch the inactivation phenotype conferred to CaV2.3 from slow to fast after posttranslational modifications during channel biogenesis, modulation mechanism, overview | ? | - |
? | |
additional information | Rattus norvegicus | the voltage-gated calcium channel beta2a contains a conserved guanylate kinase domain, which is alone recapitulating calcium channel beta-subunit CaVbeta-mediated modulation of channel activation inhibiting inactivation of the voltage-gated channel. CaVbeta can switch the inactivation phenotype conferred to CaV2.3 from slow to fast after posttranslational modifications during channel biogenesis, modulation mechanism, overview | ? | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Rattus norvegicus | - |
- |
- |
Rattus norvegicus | Q8VGC3 | Cavbeta2a | - |
Renatured (Comment) | Organism |
---|---|
recombinant Cavbeta1b after overexpression in inclusion bodies in Xenopus laevis oocytes | Rattus norvegicus |
recombinant Cavbeta2a from inclusion bodies after overexpression in Xenopus laevis oocytes | Rattus norvegicus |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
additional information | the voltage-gated calcium channel beta1b contains a conserved guanylate kinase domain, which is alone recapitulating calcium channel beta-subunit CaVbeta-mediated modulation of channel activation facilitating inactivation of the voltage-gated channel. CaVbeta can switch the inactivation phenotype conferred to CaV2.3 from slow to fast after posttranslational modifications during channel biogenesis, modulation mechanism, overview | Rattus norvegicus | ? | - |
? | |
additional information | the voltage-gated calcium channel beta2a contains a conserved guanylate kinase domain, which is alone recapitulating calcium channel beta-subunit CaVbeta-mediated modulation of channel activation inhibiting inactivation of the voltage-gated channel. CaVbeta can switch the inactivation phenotype conferred to CaV2.3 from slow to fast after posttranslational modifications during channel biogenesis, modulation mechanism, overview | Rattus norvegicus | ? | - |
? |
Subunits | Comment | Organism |
---|---|---|
dimer | the recombinant refolded CaVbeta2a-GK is essentially a dimer | Rattus norvegicus |
monomer or dimer | the recombinant and refolded CaVbeta1b-GK is a mixture of dimers and monomers | Rattus norvegicus |
Synonyms | Comment | Organism |
---|---|---|
Cavbeta1b | - |
Rattus norvegicus |
Cavbeta2a | - |
Rattus norvegicus |
voltage-gated calcium channel beta1b | - |
Rattus norvegicus |
voltage-gated calcium channel beta2a | - |
Rattus norvegicus |