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Literature summary for 2.7.4.8 extracted from
- Inhibition of rat hepatic guanylate kinase by 6-thioguanosine-5-phosphate and 6-selenoguanosine-5-phosphate (1975), Biochem. Pharmacol., 24, 791-795.
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| 6-Selenoguanosine 5'-phosphate | GMP-phosphorylation, pI 4.9-isozyme, competitive with respect to GMP | Rattus norvegicus |  |
| 6-Thioguanosine 5'-phosphate | GMP-phosphorylation, pI 4.9-isozyme, competitive with respect to GMP | Rattus norvegicus | |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Rattus norvegicus | - |
- |
- |
Purification (Commentary)
| Purification (Comment) | Organism |
|---|---|
| partial | Rattus norvegicus |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| liver | - |
Rattus norvegicus | - |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| ATP + 8-azaguanosine 5'-monophosphate | - |
Rattus norvegicus | ADP + 8-azaguanosine 5'-diphosphate | - |
? | |
| ATP + dGMP | - |
Rattus norvegicus | ADP + dGDP | - |
r | |
| dATP + dGMP | - |
Rattus norvegicus | dADP + dGDP | - |
? | |
| dATP + GMP | - |
Rattus norvegicus | dADP + GDP | - |
? | |
pI Value
| Organism | Comment | pI Value Maximum | pI Value |
|---|---|---|---|
| Rattus norvegicus | 3 isoelectric variants | 4.8 | 4.7 |
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