Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
mitochondrion | located in the mitochondrial intermembrane/cristae space | Homo sapiens | 5739 | - |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | O00746 | - |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
bladder | highest expression | Homo sapiens | - |
kidney | highest expression | Homo sapiens | - |
liver | highest expression | Homo sapiens | - |
additional information | HeLa cells are naturally almost devoid of NDPK-D | Homo sapiens | - |
prostate | highest expression | Homo sapiens | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
ATP + NDP | - |
Homo sapiens | ADP + NTP | - |
? |
Subunits | Comment | Organism |
---|---|---|
hexamer | x-ray crystallography | Homo sapiens |
Synonyms | Comment | Organism |
---|---|---|
NDPK-D | mitochondrial isoform of nucleoside diphosphate kinase | Homo sapiens |
nucleoside diphosphate kinase | - |
Homo sapiens |
Cofactor | Comment | Organism | Structure |
---|---|---|---|
ATP | - |
Homo sapiens |
General Information | Comment | Organism |
---|---|---|
physiological function | NDPK-D is proposed to couple ATP export through adenine nucleotide translocator to the synthesis of the other nucleoside triphosphates e.g. GTP | Homo sapiens |