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Literature summary for 2.7.4.6 extracted from

  • Verslues, P.E.; Batelli, G.; Grillo, S.; Agius, F.; Kim, Y.S.; Zhu, J.; Agarwal, M.; Katiyar-Agarwal, S.; Zhu, J.K.
    Interaction of SOS2 with nucleoside diphosphate kinase 2 and catalases reveals a point of connection between salt stress and H2O2 signaling in Arabidopsis thaliana (2007), Mol. Cell. Biol., 27, 7771-7780.
    View publication on PubMedView publication on EuropePMC
Search for more literature for 2.7.4.6

Cloned(Commentary)

Cloned (Comment) Organism
gene ndpk2, expression of GST-tagged wild-type enzyme in Escherichia coli, expression of SOS2 and NDPK2 in Saccharomyces cerevisiae in the two-hybrid system Arabidopsis thaliana

Protein Variants

Protein Variants Comment Organism
additional information a ndpk2 knockout mutant shows increased salt stress sensitivity compared to the wild-type enzyme. The sos2-2/ndpk2 double mutant is more salt sensitive than a sos2-2 single mutant, and does not hyperaccumulate H2O2 in response to salt stress Arabidopsis thaliana

Inhibitors

Inhibitors Comment Organism Structure
additional information SOS2, a class 3 sucrose-nonfermenting 1-related kinase, interacts with the H2O2 signaling protein NDPK2 and inhibits its autophosphorylation activity Arabidopsis thaliana

Metals/Ions

Metals/Ions Comment Organism Structure
Mg2+
-
 Arabidopsis thaliana

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
additional information Arabidopsis thaliana NDPK2 is a H2O2 signaling protein that performs autophosphorylation. NDPK2 and H2O2 are involved in salt resistance, overview ?
-
 ?

Organism

Organism UniProt Comment Textmining
Arabidopsis thaliana
-
 gene ndpk2
-

Posttranslational Modification

Posttranslational Modification Comment Organism
phosphoprotein NDPK2 performs autophosphorylation Arabidopsis thaliana

Purification (Commentary)

Purification (Comment) Organism
recombinant GST-tagged wild-type enzyme from Escherichia coli by glutathione affinity chromatography Arabidopsis thaliana

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
additional information NDPK2 is a H2O2 signaling protein that performs autophosphorylation. NDPK2 and H2O2 are involved in salt resistance, overview Arabidopsis thaliana ?
-
 ?

Temperature Optimum [°C]

Temperature Optimum [°C] Temperature Optimum Maximum [°C] Comment Organism
30
-
 assay at Arabidopsis thaliana

pH Optimum

pH Optimum Minimum pH Optimum Maximum Comment Organism
8
-
 assay at Arabidopsis thaliana