Protein Variants | Comment | Organism |
---|---|---|
R90D | site-directed mutagenesis, the mutant does not bind to cardiolipin | Homo sapiens |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
mitochondrial inner membrane | structural basis of NDPK-D/mitochondrial membrane interactions via binding of cardiolipin, overview | Homo sapiens | 5743 | - |
mitochondrial inner membrane | structural basis of NDPK-D/mitochondrial membrane interactions, overview | Rattus norvegicus | 5743 | - |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
ATP + TDP | Rattus norvegicus | - |
ADP + TTP | - |
r | |
ATP + TDP | Homo sapiens | - |
ADP + TTP | - |
r |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | O00746 | gene NME4 encoding isozyme NDPK-D | - |
Rattus norvegicus | - |
male Wistar rats, isozyme NDPK-D | - |
Purification (Comment) | Organism |
---|---|
native enzyme partially by mitochondrion preparation | Rattus norvegicus |
native enzyme partially by mitochondrion preparation | Homo sapiens |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
HEK-293 cell | - |
Homo sapiens | - |
HeLa cell | - |
Homo sapiens | - |
liver | - |
Rattus norvegicus | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
ATP + TDP | - |
Rattus norvegicus | ADP + TTP | - |
r | |
ATP + TDP | - |
Homo sapiens | ADP + TTP | - |
r | |
ATP + TDP | the enzyme activity depends largely upon the membrane-bound state | Rattus norvegicus | ADP + TTP | - |
r | |
ATP + TDP | the enzyme activity depends largely upon the membrane-bound state | Homo sapiens | ADP + TTP | - |
r |
Synonyms | Comment | Organism |
---|---|---|
NDPK-D | - |
Rattus norvegicus |
NDPK-D | - |
Homo sapiens |
NM23-H4 | - |
Homo sapiens |
nucleoside diphosphate kinase D | - |
Rattus norvegicus |
nucleoside diphosphate kinase D | - |
Homo sapiens |