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Literature summary for 2.7.4.3 extracted from

  • Luz, C.M.; König, I.; Schirmer, R.H.; Frank, R.
    Human cytosolic adenylate kinase allelozymes; purification and characterization (1990), Biochim. Biophys. Acta, 1038, 80-84.
    View publication on PubMed
Search for more literature for 2.7.4.3

General Stability

General Stability Organism
diadenosine pentaphosphate, i.e. AP5A, stabilizes during preparative electrophoresis Homo sapiens

KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
0.05
-
 ADP
-
 Homo sapiens
0.15
-
 2 ADP ADP in form of MgADP- Homo sapiens
0.18
-
 AMP
-
 Homo sapiens
0.23
-
 ATP ATP in form of MgATP2- Homo sapiens

Localization

Localization Comment Organism GeneOntology No. Textmining
cytosol
-
 Homo sapiens 5829
-

Metals/Ions

Metals/Ions Comment Organism Structure
Mg2+ requirement Homo sapiens

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
 post mortem
-
Homo sapiens
-
 heterozygote
-

Purification (Commentary)

Purification (Comment) Organism
2 allelozymes: AK1*1 and AK1*2 Homo sapiens
separable by electrophoresis, not by isoelectric focusing Homo sapiens

Source Tissue

Source Tissue Comment Organism Textmining
muscle
-
 Homo sapiens
-

Specific Activity [micromol/min/mg]

Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
420
-
 allelozyme AK1*2 Homo sapiens
1480
-
 allelozyme AK1*1 Homo sapiens

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2 ADP
-
 Homo sapiens ATP + AMP
-
 ?
ATP + AMP
-
 Homo sapiens ADP + ADP
-
 ?
ATP + AMP
-
 Homo sapiens 2 ADP
-
 ?

Turnover Number [1/s]

Turnover Number Minimum [1/s] Turnover Number Maximum [1/s] Substrate Comment Organism Structure
152
-
 ATP allelozyme AK1*2 Homo sapiens