Inhibitors | Comment | Organism | Structure |
---|---|---|---|
ATP | above 10 mM | Saccharomyces cerevisiae |
Metals/Ions | Comment | Organism | Structure |
---|---|---|---|
Co2+ | can partially replace Mg2+ in activation | Saccharomyces cerevisiae | |
Fe2+ | can partially replace Mg2+ in activation | Saccharomyces cerevisiae | |
Mg2+ | divalent cation required, Mg2+ most efficient | Saccharomyces cerevisiae | |
Mn2+ | can partially replace Mg2+ in activation | Saccharomyces cerevisiae | |
Zn2+ | can partially replace Mg2+ in activation | Saccharomyces cerevisiae |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
ATP + (R)-5-phosphomevalonate | Saccharomyces cerevisiae | - |
ADP + 5-diphosphomevalonate | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Saccharomyces cerevisiae | - |
- |
- |
Purification (Comment) | Organism |
---|---|
ammonium sulfate, ethanol, phosphate gel, DEAE-cellulose | Saccharomyces cerevisiae |
Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
---|---|---|---|
0.06 | - |
- |
Saccharomyces cerevisiae |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
ATP + (R)-5-phosphomevalonate | - |
Saccharomyces cerevisiae | ADP + 5-diphosphomevalonate | - |
? | |
ATP + 5-phosphomevalonate | maximal activity at 10 mM ATP | Saccharomyces cerevisiae | ADP + 5-diphosphomevalonate | - |
? |
pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
---|---|---|---|
5.5 | 10 | - |
Saccharomyces cerevisiae |