Literature summary for 2.7.4.1 extracted from

Diaz, M.; Sevillano, L.; Rico, S.; Lombo, F.; Brana, A.F.; Salas, J.A.; Mendez, C.; Santamaria, R.I.
High level of antibiotic production in a double polyphosphate kinase and phosphate-binding protein mutant of Streptomyces lividans (2013), FEMS Microbiol. Lett., 342, 123-129.

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Cloned(Commentary)

Cloned (Comment)	Organism
expressed in Streptomyces lividans	Streptomyces lividans

Organism

Organism	UniProt	Comment	Textmining
Streptomyces lividans	-	-	-
Streptomyces lividans TK24	-	-	-

Synonyms

Synonyms	Comment	Organism
PPK	-	Streptomyces lividans

General Information

General Information	Comment	Organism
malfunction	under phosphate limitation conditions, the double polyphosphate kinase/phosphate-binding protein mutant shows a higher production of the endogenous antibiotic actinorhodin and the heterologous antitumor 8-demethyl-tetracenomycin (up to 10fold with respect to the wild type strain)	Streptomyces lividans

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Release 2023.1 (January 2023)