Activating Compound | Comment | Organism | Structure |
---|---|---|---|
ATP | about 80% of the activity formerly inhibited by phenylglyoxal is retained by incubating with 20 mM ATP | Locusta migratoria manilensis | |
dithiothreitol | once treated with 5,5'-dithiobis-2-nitrobenzoic acid, the enzyme activity can be recovered more than 95% after incubation for 20 min with 0.15 mM dithiothreitol | Locusta migratoria manilensis |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
5,5'-dithiobis-2-nitrobenzoic acid | - |
Locusta migratoria manilensis | |
DTNB | the arginine kinase modified by DTNB can be fully reactivated by dithiothreitol in a monophasic kinetic course. This reactivation can be slowed down in the presence of ATP, suggesting that the essential Cys is located near the ATP binding site | Locusta migratoria manilensis | |
Phenylglyoxal | the enzyme loses 84.7% of its initial activity after incubation for 90 min with 0.0009 mM phenyllyoxal | Locusta migratoria manilensis |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Locusta migratoria manilensis | - |
- |
- |
Renatured (Comment) | Organism |
---|---|
the arginine kinase modified by DTNB can be fully reactivated by dithiothreitol in a monophasic kinetic course | Locusta migratoria manilensis |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
muscle | - |
Locusta migratoria manilensis | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
ATP + L-Arg | - |
Locusta migratoria manilensis | ADP + Nomega-phospho-L-Arg | - |
r |