Any feedback?
Literature summary for 2.7.3.2 extracted from
- Oxidative stress mediated the inhibition of cerebral creatine kinase activity in silver catfish fed with aflatoxin B1-contaminated diet (2019), Fish Physiol. Biochem., 45, 63-70 .
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| additional information | brain creatine kinase activity is lower on days 14 and 21 post-feeding in animals that receive aflatoxin B1-contaminated diet compared to the control group. The inhibition of brain enzyme activity appears to be mediated by the oxidation of lipids, proteins, and thiol group, as well as by a reduction in the antioxidant capacity | Rhamdia quelen |
Natural Substrates/ Products (Substrates)
| Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| ATP + creatine | Rhamdia quelen | - |
ADP + phosphocreatine | - |
? |  |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Rhamdia quelen | - |
silver catfish | - |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| brain | - |
Rhamdia quelen | - |
| telencephalon | - |
Rhamdia quelen | - |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| ADP + phosphocreatine | - |
Rhamdia quelen | ATP + creatine | - |
? | |
| ATP + creatine | - |
Rhamdia quelen | ADP + phosphocreatine | - |
? | |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| creatinine kinase | - |
Rhamdia quelen |
Cofactor
| Cofactor | Comment | Organism | Structure |
|---|---|---|---|
| ATP | - |
Rhamdia quelen | |
Expression
| Organism | Comment | Expression |
|---|---|---|
| Rhamdia quelen | brain enzyme activity is lower on days 14 and 21 post-feeding in animals that received aflatoxin B1-contaminated diet compared to the control group | down |
General Information
| General Information | Comment | Organism |
|---|---|---|
| physiological function | the essential enzyme plays an important role in brain energy homeostasis | Rhamdia quelen |
| physiological function | the enzyme plays an important role in brain energy homeostasis | Rhamdia quelen |
Use of this online version of BRENDA is free under the CC BY 4.0 license. See terms of use for full details.
Release 2023.1 (January 2023)
Legal
Curated at
Member of
