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Literature summary for 2.7.2.8 extracted from

  • Pauwels, K.; Abadjieva, A.; Hilven, P.; Stankiewicz, A.; Crabeel, M.
    The N-acetylglutamate synthase/N-acetylglutamate kinase metabolon of Saccharomyces cerevisiae allows co-ordinated feedback regulation of the first two steps in arginine biosynthesis (2003), Eur. J. Biochem., 270, 1014-1024.
    View publication on PubMed

Inhibitors

Inhibitors Comment Organism Structure
arginine feedback regulation of enzyme and N-acetylglutamate synthase is mutually interdependent, enzymes form a complex Saccharomyces cerevisiae

Organism

Organism UniProt Comment Textmining
Saccharomyces cerevisiae
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Reaction

Reaction Comment Organism Reaction ID
ATP + N-acetyl-L-glutamate = ADP + N-acetyl-L-glutamyl 5-phosphate enzyme has to interact stoichiometrically with acetylglutamate synthase in order to be active Saccharomyces cerevisiae