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Literature summary for 2.7.2.4 extracted from

  • Veron, M.; Falcoz-Kelly, F.; Cohen, G.N.
    The threonine-sensitive homoserine dehydrogenase and aspartokinase activities of Escherichia coli K12. The two catalytic activities are carried by two independent regions of the polypeptide chain (1972), Eur. J. Biochem., 28, 520-527.
    View publication on PubMed
Search for more literature for 2.7.2.4

Inhibitors

Inhibitors Comment Organism Structure
L-threonine
-
 Escherichia coli

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
48000
-
 4 * 48000, SDS-PAGE Escherichia coli
180000 200000 aspartokinase devoid of homoserine dehydrogenase activity in presence of threonine, gel filtration Escherichia coli

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
ATP + L-aspartate Escherichia coli
-
 ADP + 4-phospho-L-aspartate
-
 r

Organism

Organism UniProt Comment Textmining
Escherichia coli
-
 Tir 8, derepressed strain of K 12 and mutant Gif 108
-

Purification (Commentary)

Purification (Comment) Organism
aspartokinase devoid of homoserine dehydrogenase activity extracted from mutant Gif 108 Escherichia coli

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
ATP + L-aspartate
-
 Escherichia coli ADP + 4-phospho-L-aspartate
-
 r
additional information
-
 Escherichia coli ?
-
 ?

Subunits

Subunits Comment Organism
tetramer 4 * 48000, SDS-PAGE Escherichia coli

Synonyms

Synonyms Comment Organism
aspartokinase 1-homoserine dehydrogenase 1
-
 Escherichia coli