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Literature summary for 2.7.2.3 extracted from
- PGK1, the gene encoding the glycolitic enzyme phosphoglycerate kinase, acts as a multicopy suppressor of apoptotic phenotypes in S. cerevisiae (2009), Yeast, 26, 31-37.
Cloned(Commentary)
| Cloned (Comment) | Organism |
|---|---|
| pRS313/Kllsm4DELTA1 plasmid, carrying a truncated form of the KlLSM4 gene of Kluyveromyces lactis introduced into yeast strain MCY4. Overexpression of the glycolitic gene PGK1 in MCY4/313Kllsm4DELTA1 | Saccharomyces cerevisiae |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Saccharomyces cerevisiae | - |
- |
- |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| PGK1 | - |
Saccharomyces cerevisiae |
| phosphoglycerate kinase | - |
Saccharomyces cerevisiae |
General Information
| General Information | Comment | Organism |
|---|---|---|
| physiological function | overexpression of PGK1 can restore normal ageing of cells and suppress other apoptotic phenotypes of the MCY4/313Kllsm4DELTA1 mutant strain, including chromatin fragmentation and sensitivity to acetic acid, H2O2 and caffeine | Saccharomyces cerevisiae |
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