Inhibitors | Comment | Organism | Structure |
---|---|---|---|
2-(p-Sulfophenylazo)-1,8-dihydroxy-3,6-naphthalene disulfonic acid | competitive against MgATP2- and 3-phospho-D-glycerate | Saccharomyces cerevisiae | |
Hexametaphosphate | competitive against 3-phospho-D-glycerate and noncompetitive against MgATP2- | Saccharomyces cerevisiae | |
hydroxyethylidene bisphosphonic acid | competitive against MgATP2- and 3-phospho-D-glycerate | Saccharomyces cerevisiae | |
Naphthalene-1,3,6-trisulfonic acid | competitive against 3-phospho-D-glycerate and noncompetitive against MgATP2-, binding structure | Saccharomyces cerevisiae | |
suramin | competitive against MgATP2- and 3-phospho-D-glycerate | Saccharomyces cerevisiae |
Metals/Ions | Comment | Organism | Structure |
---|---|---|---|
Mg2+ | required | Saccharomyces cerevisiae |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Saccharomyces cerevisiae | - |
commercial product | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
ATP + 3-phospho-D-glycerate | - |
Saccharomyces cerevisiae | ADP + 1,3-diphosphoglycerate | - |
r |
Cofactor | Comment | Organism | Structure |
---|---|---|---|
ADP | - |
Saccharomyces cerevisiae | |
ATP | true substrate is the magnesium complexes of ATP | Saccharomyces cerevisiae | |
ATP | required as phosphate donor | Saccharomyces cerevisiae |
Ki Value [mM] | Ki Value maximum [mM] | Inhibitor | Comment | Organism | Structure |
---|---|---|---|---|---|
0.1 | - |
2-(p-Sulfophenylazo)-1,8-dihydroxy-3,6-naphthalene disulfonic acid | pH 7.5, versus 3-phospho-D-glycerate | Saccharomyces cerevisiae | |
0.13 | - |
suramin | pH 7.5, versus MgATP2- | Saccharomyces cerevisiae | |
0.15 | - |
2-(p-Sulfophenylazo)-1,8-dihydroxy-3,6-naphthalene disulfonic acid | pH 7.5, versus MgATP2- | Saccharomyces cerevisiae | |
0.16 | - |
suramin | pH 7.5, versus 3-phospho-D-glycerate | Saccharomyces cerevisiae | |
1.28 | - |
Hexametaphosphate | pH 7.5, versus 3-phospho-D-glycerate | Saccharomyces cerevisiae | |
5.5 | - |
Naphthalene-1,3,6-trisulfonic acid | pH 7.5, versus 3-phospho-D-glycerate | Saccharomyces cerevisiae | |
23 | - |
hydroxyethylidene bisphosphonic acid | pH 7.5, versus MgATP2- | Saccharomyces cerevisiae | |
25 | - |
hydroxyethylidene bisphosphonic acid | pH 7.5, versus 3-phospho-D-glycerate | Saccharomyces cerevisiae |