Literature summary for 2.7.2.3 extracted from

Schulman, M.D.; Valentino, D.
Purification and characterization of phosphoglycerate kinase from Fasciola hepatica (1981), Mol. Biochem. Parasitol., 2, 309-321.

Search for more literature for 2.7.2.3

Inhibitors

Inhibitors	Comment	Organism	Structure
5,5'-dithiobis(2-nitrobenzoic acid)	reversible	Fasciola hepatica
ADP	noncompetitive with respect to ATP and 3-phospho-D-glycerate	Fasciola hepatica
iodoacetamide	irreversible	Fasciola hepatica
N-ethylmaleimide	irreversible	Fasciola hepatica
p-chloromercuribenzoate	reversible	Fasciola hepatica

KM Value [mM]

KM Value [mM]	KM Value Maximum [mM]	Substrate	Comment	Organism	Structure
0.9	-	ATP	-	Fasciola hepatica
1.26	-	3-phospho-D-glycerate	-	Fasciola hepatica

Molecular Weight [Da]

Molecular Weight [Da]	Molecular Weight Maximum [Da]	Comment	Organism
47900	-	sedimentation equilibrium method	Fasciola hepatica

Organism

Organism	UniProt	Comment	Textmining
Fasciola hepatica	-	-	-

Purification (Commentary)

Purification (Comment)	Organism
375fold to homogeneity	Fasciola hepatica

Reaction

Reaction	Comment	Organism	Reaction ID
ATP + 3-phospho-D-glycerate = ADP + 3-phospho-D-glyceroyl phosphate	sequential mechanism	Fasciola hepatica	a

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
ATP + 3-phospho-D-glycerate	-	Fasciola hepatica	ADP + 1,3-diphosphoglycerate	-	r

Subunits

Subunits	Comment	Organism
monomer	1 * 47900, SDS-PAGE	Fasciola hepatica

Cofactor

Cofactor	Comment	Organism	Structure
ADP	-	Fasciola hepatica
ATP	required as phosphate donor	Fasciola hepatica

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Release 2023.1 (January 2023)