Inhibitors | Comment | Organism | Structure |
---|---|---|---|
additional information | inhibitor design using the the structure of the catalytic intermediate | Escherichia coli | |
trifluoroethanol | leads to reduced growth and acetate content, binding mode by molecular docking | Escherichia coli | |
trifluoroethyl butyrate | leads to reduced growth and acetate content, binding mode by molecular docking | Escherichia coli |
Metals/Ions | Comment | Organism | Structure |
---|---|---|---|
Mg2+ | required | Escherichia coli |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
ATP + acetate | Escherichia coli | - |
ADP + acetyl phosphate | - |
r |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Escherichia coli | P0A6A3 | PTCC 1399 | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
ATP + acetate | - |
Escherichia coli | ADP + acetyl phosphate | - |
r |
Cofactor | Comment | Organism | Structure |
---|---|---|---|
ADP | - |
Escherichia coli | |
ATP | - |
Escherichia coli |
General Information | Comment | Organism |
---|---|---|
additional information | construction of the three-dimensional structure of the Escherichia coli acetate kinase by use of molecular homology modeling using the structure of the enzyme from Thermotoga maritima, overview | Escherichia coli |