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Literature summary for 2.7.13.3 extracted from

  • Barba-Ostria, C.; Lledias, F.; Georgellis, D.
    The Neurospora crassa DCC-1 protein, a putative histidine kinase, is required for normal sexual and asexual development and carotenogenesis (2011), Eukaryot. Cell, 10, 1733-1739.
    View publication on PubMedView publication on EuropePMC
Search for more literature for 2.7.13.3

Cloned(Commentary)

Cloned (Comment) Organism
gene NCU00939 Neurospora crassa

Organism

Organism UniProt Comment Textmining
Neurospora crassa Q7SFA8
-
-
Neurospora crassa 74-ORS-6a Q7SFA8
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-

Source Tissue

Source Tissue Comment Organism Textmining
mycelium
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 Neurospora crassa
-

Synonyms

Synonyms Comment Organism
DCC-1 protein
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 Neurospora crassa
development and carotenogenesis control-1 protein UniProt Neurospora crassa
NCU00939
-
 Neurospora crassa

General Information

General Information Comment Organism
malfunction in contrast to the wild-type strain, which forms mature pigmented perithecia, only an insignificant number of small unpigmented mutant fruiting bodies are observed in the dcc-1 deletion mutant, thus deletion of dcc-1 leads to sterility. Supplementation with cAMP does not restore the sexual defects (formation of submerged perithecia) of the DELTAdcc-1 mutant Neurospora crassa
physiological function two-component signaling pathways are based on phosphoryl group transfer between histidine kinase and response regulator proteins and regulate environmental responses. The DCC-1 protein in Neurospora crasse protein participates in the regulation of processes such as conidiation, perithecial development, and, to a certain degree, carotenogenesis. DCC-1 exerts its effect by promoting cyclic AMP production, including GNA-3 and CR-1, thereby placing this protein within the context of a signaling pathway that operates during conidiation and sexual development. The DCC-1 histidine kinase is required for proper perithecial development, it has a significant role as a negative regulator of sporulation during vegetative growth Neurospora crassa