Protein Variants | Comment | Organism |
---|---|---|
A143G | the mutant still has some divalent cation-mediated repression and therefore likely has some ability to bind cations | Pseudomonas aeruginosa |
A143G | the mutant still has some divalent cation-mediated repression and therefore likely have some ability to bind cations | Salmonella enterica subsp. enterica serovar Typhimurium |
D110A | the mutant exhibits strong de-repression in medium containing 10 mM Mg2+, and activity is approximately the same regardless of the cation content in the growth medium | Salmonella enterica subsp. enterica serovar Typhimurium |
D110A | the mutant exhibits strong de-repression in medium containing 10 mM Mg2+, and activity is approximately the same regardless of the cation content in the growth medium | Pseudomonas aeruginosa |
D131A | the mutant exhibits strong de-repression in medium containing 10 mM Mg2+, and activity is approximately the same regardless of the cation content in the growth medium | Salmonella enterica subsp. enterica serovar Typhimurium |
D131A | the mutant exhibits strong de-repression in medium containing 10 mM Mg2+, and activity is approximately the same regardless of the cation content in the growth medium | Pseudomonas aeruginosa |
D131A | the purified mutant enzyme shows no fluorescence change well into the mM range of Mg2+, suggesting that this mutation renders the protein incapable of binding Mg2+ | Salmonella enterica subsp. enterica serovar Typhimurium |
D131A | the purified mutant enzyme shows no fluorescence change well into the mM range of Mg2+, suggesting that this mutation renders the protein incapable of binding Mg2+ | Pseudomonas aeruginosa |
E115A | the mutant still has some divalent cation-mediated repression and therefore likely has some ability to bind cations | Pseudomonas aeruginosa |
E115A | the mutant still has some divalent cation-mediated repression and therefore likely have some ability to bind cations | Salmonella enterica subsp. enterica serovar Typhimurium |
E133A | the mutant exhibits strong de-repression in medium containing 10 mM Mg2+, and activity is approximately the same regardless of the cation content in the growth medium | Salmonella enterica subsp. enterica serovar Typhimurium |
E133A | the mutant exhibits strong de-repression in medium containing 10 mM Mg2+, and activity is approximately the same regardless of the cation content in the growth medium | Pseudomonas aeruginosa |
E77A | the mutant still has some divalent cation-mediated repression and therefore likely has some ability to bind cations | Pseudomonas aeruginosa |
E77A | the mutant still has some divalent cation-mediated repression and therefore likely have some ability to bind cations | Salmonella enterica subsp. enterica serovar Typhimurium |
G139A | the mutant still has some divalent cation-mediated repression and therefore likely has some ability to bind cations | Pseudomonas aeruginosa |
G139A | the mutant still has some divalent cation-mediated repression and therefore likely have some ability to bind cations | Salmonella enterica subsp. enterica serovar Typhimurium |
L137A | the mutant exhibits strong de-repression in medium containing 10 mM Mg2+, and activity is approximately the same regardless of the cation content in the growth medium | Salmonella enterica subsp. enterica serovar Typhimurium |
L137A | the mutant exhibits strong de-repression in medium containing 10 mM Mg2+, and activity is approximately the same regardless of the cation content in the growth medium | Pseudomonas aeruginosa |
L158A | the mutant exhibits strong de-repression in medium containing 10 mM Mg2+, and activity is approximately the same regardless of the cation content in the growth medium | Salmonella enterica subsp. enterica serovar Typhimurium |
L158A | the mutant exhibits strong de-repression in medium containing 10 mM Mg2+, and activity is approximately the same regardless of the cation content in the growth medium | Pseudomonas aeruginosa |
S145A | the mutant exhibits strong de-repression in medium containing 10 mM Mg2+, and activity is approximately the same regardless of the cation content in the growth medium | Salmonella enterica subsp. enterica serovar Typhimurium |
S145A | the mutant exhibits strong de-repression in medium containing 10 mM Mg2+, and activity is approximately the same regardless of the cation content in the growth medium | Pseudomonas aeruginosa |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
Ca2+ | - |
Pseudomonas aeruginosa | |
Ca2+ | - |
Salmonella enterica subsp. enterica serovar Typhimurium | |
Mg2+ | PhoQ is strongly repressed in divalent cation-replete medium at 10 mM Mg2+ | Pseudomonas aeruginosa | |
Mg2+ | PhoQ is strongly repressed in divalent cation-replete medium at 10 mM Mg2+ | Salmonella enterica subsp. enterica serovar Typhimurium |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
membrane | - |
Salmonella enterica subsp. enterica serovar Typhimurium | 16020 | - |
membrane | - |
Pseudomonas aeruginosa | 16020 | - |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Pseudomonas aeruginosa | - |
- |
- |
Salmonella enterica subsp. enterica serovar Typhimurium | - |
- |
- |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
ATP + PhoN protein L-histidine | - |
Salmonella enterica subsp. enterica serovar Typhimurium | ADP + PhoN protein N-phospho-L-histidine | - |
? | |
ATP + PhoN protein L-histidine | - |
Pseudomonas aeruginosa | ADP + PhoN protein N-phospho-L-histidine | - |
? |
Synonyms | Comment | Organism |
---|---|---|
PhoQ | - |
Salmonella enterica subsp. enterica serovar Typhimurium |
PhoQ | - |
Pseudomonas aeruginosa |
sensor histidine kinase | - |
Salmonella enterica subsp. enterica serovar Typhimurium |
sensor histidine kinase | - |
Pseudomonas aeruginosa |
Cofactor | Comment | Organism | Structure |
---|---|---|---|
ATP | - |
Salmonella enterica subsp. enterica serovar Typhimurium | |
ATP | - |
Pseudomonas aeruginosa |
Organism | Comment | Expression |
---|---|---|
Salmonella enterica subsp. enterica serovar Typhimurium | PhoQ is activated by acidic pH (pH 5.5) | up |
Pseudomonas aeruginosa | PhoQ is activated by acidic pH (pH 5.5) | up |