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Literature summary for 2.7.13.3 extracted from
- Requirement of histidine kinases HP0165 and HP1364 for acid resistance in Helicobacter pylori (2006), Infect. Immun., 74, 3052-3059.
Application
| Application | Comment | Organism |
|---|---|---|
| additional information | intact HP0165 and HP1364 histidine kinases are required for acid resistance in Helicobacter pylori | Helicobacter pylori |
Cloned(Commentary)
| Cloned (Comment) | Organism |
|---|---|
| into vector pGEM-T, then cloned genes disrupted in HP0244, HP1364, and HP0165 sequences. The resulting plasmids, which are unable to replicate in Helicobacter pylori, introduced into Helicobacter pylori J99 | Helicobacter pylori |
Protein Variants
| Protein Variants | Comment | Organism |
|---|---|---|
| additional information | growth of HP0244 mutant strain is similar to the growth of the wild-type strain, null mutations in either HP0165 or HP1364 histidine kinases are impaired in their ability to grow at pH 5.0, acid-responsive gene transcription is altered in the HP0165 and HP1364 null mutant strains compared to the parental wild-type strain, growth of complemented mutant strains is similar to that of the wild-type strain | Helicobacter pylori |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Helicobacter pylori | - |
- |
- |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| histidine kinase | - |
Helicobacter pylori |
| HP0165 | - |
Helicobacter pylori |
| HP1364 | - |
Helicobacter pylori |
pH Range
| pH Minimum | pH Maximum | Comment | Organism |
|---|---|---|---|
| 5 | 7 | - |
Helicobacter pylori |
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