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BRENDA support

Literature summary for 2.7.13.3 extracted from

  • Gilmour, R.; Foster, J.E.; Sheng, Q.; McClain, J.R.; Riley, A.; Sun, P.M.; Ng, W.L.; Yan, D.; Nicas, T.I.; Henry, K.; Winkler, M.E.
    New class of competitive inhibitor of bacterial histidine kinases (2005), J. Bacteriol., 187, 8196-8200.
    View publication on PubMedView publication on EuropePMC

Inhibitors

Inhibitors Comment Organism Structure
3,6-diamino-5-cyano-4-phenyl-thieno[2,3-b]pyridine-2-carboxylic acid (4-bromo-phenyl)amide competitive inhibitor of the coupled reaction of histidine kinase HpkA HK and the cognate response regulator DrrA RR Thermotoga maritima
AMP-PNP
-
Thermotoga maritima

Organism

Organism UniProt Comment Textmining
Thermotoga maritima
-
-
-

Synonyms

Synonyms Comment Organism
HpkA HK
-
Thermotoga maritima

Ki Value [mM]

Ki Value [mM] Ki Value maximum [mM] Inhibitor Comment Organism Structure
0.00062
-
3,6-diamino-5-cyano-4-phenyl-thieno[2,3-b]pyridine-2-carboxylic acid (4-bromo-phenyl)amide
-
Thermotoga maritima
0.1
-
AMP-PNP
-
Thermotoga maritima