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Literature summary for 2.7.11.1 extracted from

  • Greer, Y.; Westlake, C.; Gao, B.; Bharti, K.; Shiba, Y.; Xavier, C.; Pazour, G.; Yang, Y.; Rubin, J.
    Casein kinase 1delta functions at the centrosome and Golgi to promote ciliogenesis (2014), Mol. Biol. Cell, 25, 1629-1640.
    View publication on PubMedView publication on EuropePMC
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Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
ATP + Rab8a protein Mus musculus
-
 ADP + phosphorylated Rab8a protein
-
 ?

Organism

Organism UniProt Comment Textmining
Mus musculus
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
MEF cell
-
 Mus musculus
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
ATP + Rab8a protein
-
 Mus musculus ADP + phosphorylated Rab8a protein
-
 ?

Synonyms

Synonyms Comment Organism
casein kinase 1delta
-
 Mus musculus
CK1delta
-
 Mus musculus

General Information

General Information Comment Organism
malfunction enzyme inhibition disrupts cis-Golgi organization, intraflagellar transport protein 20 distribution, and Golgi-derived microtubule nucleation Mus musculus
physiological function the enzyme is required for microtubule nucleation at the Golgi and maintenance of Golgi integrity and promotes ciliogenesis Mus musculus