Any feedback?
Literature summary for 2.7.11.1 extracted from
- Calcium and calmodulin-dependent serine/threonine protein kinase type II (CaMKII)-mediated intramolecular opening of integrin cytoplasmic domain-associated protein-1 (ICAP-1alpha) negatively regulates beta1 integrins (2013), J. Biol. Chem., 288, 20248-20260.
Metals/Ions
| Metals/Ions | Comment | Organism | Structure |
|---|---|---|---|
| Ca2+ | dependent on | Mus musculus |  |
Natural Substrates/ Products (Substrates)
| Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| ATP + ICAP-1alpha protein | Mus musculus | phosphorylated at threonine 38 | ADP + phosphorylated ICAP-1alpha protein | - |
? | |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Mus musculus | - |
- |
- |
Purification (Commentary)
| Purification (Comment) | Organism |
|---|---|
| protein A-coupled Sepharose bead chromatography | Mus musculus |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| ATP + ICAP-1alpha protein | phosphorylated at threonine 38 | Mus musculus | ADP + phosphorylated ICAP-1alpha protein | - |
? | |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| calcium and calmodulin-dependent serine/threonine protein kinase type II | - |
Mus musculus |
| CaMKII | - |
Mus musculus |
Cofactor
| Cofactor | Comment | Organism | Structure |
|---|---|---|---|
| Calmodulin | - |
Mus musculus | |
Use of this online version of BRENDA is free under the CC BY 4.0 license. See terms of use for full details.
Release 2023.1 (January 2023)
Legal
Curated at
Member of
