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Literature summary for 2.7.11.1 extracted from

  • Dai, J.Q.; Zhu, X.J.; Liu, F.Q.; Xiang, J.H.; Nagasawa, H.; Yang, W.J.
    Involvement of p90 ribosomal S6 kinase in termination of cell cycle arrest during development of Artemia-encysted embryos (2008), J. Biol. Chem., 283, 1705-1712.
    View publication on PubMed
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Application

Application Comment Organism
molecular biology results display the requirement of RSK activity during Artemia development and suggest its role in termination of cell cycle (G2/Mphase) arrest and promotion of mitogenesis Artemia parthenogenetica

Cloned(Commentary)

Cloned (Comment) Organism
expressed in Escherichia coli Artemia parthenogenetica

Protein Variants

Protein Variants Comment Organism
additional information in vivo knockdown of RSK activity by RNA interference, kinase inhibition, and antibody neutralization consistently induced defective larvae with distinct gaps between the exoskeleton and internal tissues. In these abnormal individuals, mitoses are detected to be largely inhibited in the affected regions Artemia parthenogenetica

Organism

Organism UniProt Comment Textmining
Artemia parthenogenetica B0EXJ4
-
-

Source Tissue

Source Tissue Comment Organism Textmining
embryo
-
 Artemia parthenogenetica
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Specific Activity [micromol/min/mg]

Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
additional information
-
 using immunochemistry, morphology, and cell cycle analysis, the identified Artemia RSK is established to be specifically activated during the post-embryonic and early larval developmental stages when arrested cells of encysted embryos resume mitoses Artemia parthenogenetica

Synonyms

Synonyms Comment Organism
p90 ribosomal S6 kinase
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 Artemia parthenogenetica
RSK
-
 Artemia parthenogenetica