Inhibitors | Comment | Organism | Structure |
---|---|---|---|
2-Aminopurine | - |
Homo sapiens |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
cytoplasm | CKalpha in normoxia | Homo sapiens | 5737 | - |
membrane | CK2beta in hypoxia | Homo sapiens | 16020 | - |
Metals/Ions | Comment | Organism | Structure |
---|---|---|---|
Mg2+ | - |
Homo sapiens |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
ATP + hypoxia-inducible factor-1 | Homo sapiens | i.e. HIF-1, casein kinase 2 inhibits the activation of HIF-1 activity by phosphorylation and thereby stabilization of the protein, CK2 is involved in and influenced by hypoxia, overview | ADP + phosphorylated hypoxia-inducible factor-1 | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
Hep-G2 cell | - |
Homo sapiens | - |
hepatoma cell | - |
Homo sapiens | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
ATP + hypoxia-inducible factor-1 | i.e. HIF-1, casein kinase 2 inhibits the activation of HIF-1 activity by phosphorylation and thereby stabilization of the protein, CK2 is involved in and influenced by hypoxia, overview | Homo sapiens | ADP + phosphorylated hypoxia-inducible factor-1 | - |
? | |
ATP + hypoxia-inducible factor-1 | i.e. HIF-1 | Homo sapiens | ADP + phosphorylated hypoxia-inducible factor-1 | - |
? |
Synonyms | Comment | Organism |
---|---|---|
casein kinase 2 | - |
Homo sapiens |
CK2 | - |
Homo sapiens |
pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
---|---|---|---|
7.5 | - |
assay at | Homo sapiens |
Cofactor | Comment | Organism | Structure |
---|---|---|---|
ATP | - |
Homo sapiens |